| 货号 | 1431/1 |
| 供应商 | Tocris |
| 生物活性 | Prototypical selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro(EC50 = 5.2 nM), and is antinociceptive in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 645.79 |
| 分子式 | C30H39N5O7S2 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 88373-73-3 |
| 序列号 | YXGFX (Modifications: X = D-Pen, Disulfide bridge between 2 - 5) |
| 参考文献 | Fraseret al (2000) Supraspinal antinociceptive response to [D-Pen2,5]-enkephalin (DPDPE) is pharmacologically distince from that to other δ-agonists in the rat. J.Pharmacol.Exp.Ther. 295 1135. PMID: 11082450. Chandrakumaret al (1992) Analogs of the δ opioid receptor selective cyclic peptide [2-D-penicillamine,5-D-penicillamine]-enkephalin: 2',6'-dimethyltyrosine and Gly3-Phe4 amide bond isostere substitutions. J.Med.Chem. 35 2928. PMID: 1323677. Clarket al (1986) [D-Pen2,D-Pen5]enkephalin (DPDPE): a δ-selective enkephalin with low affinity for μ1 opiate binding sites. Eur.J.Pharmacol. 128 303. PMID: 3025000. |