| 货号 | 3015/1 |
| 供应商 | Tocris |
| 生物活性 | Potent and selective PAR2 receptor agonist (pD2 = 7.0). Causes a dose-dependent relaxation of murine femoral arteries. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 777.96 |
| 分子式 | C36H63N11O8 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 729589-58-6 |
| 序列号 | LIGRLX (Modifications: Leu-1 = 2-Furoyl-Leu, X = Orn & C-terminal amide) |
| 参考文献 | Olianaset al (2007) Proteinase-activated receptors 1 and 2 in rat olfactory system: layer-specific regulation of multiple signaling pathways in the main olfactory bulb and induction of neurite retraction in olfactory sensory neurons. Neuroscience 146 1289. PMID: 17434682. Alshurafaet al (2004) A protease activated receptor-2 (PAR-2) activating peptide, tc-LIGRLO-NH2, induces protease release from mast cells: role in TNF degradation. BMC Pharmacol. 4 12. PMID: 15265236. McGuireet al (2004) 2-Furoyl-LIGRLO-amide: a potent and selective proteinase-activated receptor 2 agonist. J.Pharmacol.Exp.Ther. 309 1124. PMID: 14976230. |