货号 | 3136/50 |
别名 | 6-Amino-2-chloropurine riboside; 2-CADO |
供应商 | Tocris |
生物活性 | Metabolically stable analog of adenosine that behaves as an adenosine receptor agonist (Ki values are 300, 80 and 1900 nM for A1, A2A and A3 receptors respectively). Anticonvulsive in vivo. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 301.69 |
分子式 | C10H12ClN5O4 |
可溶性/溶解性 | Soluble to 25 mM in water and to 100 mM in DMSO |
CAS号 | 146-77-0 |
参考文献 | Abdul-Ghaniet al (1997) The protective effect of 2-chloroadenosine against the development of amygdala kindling and on amygdala-kindled seizures. Eur.J.Pharmacol. 326 7. PMID: 9178649. Pourgholamiet al (1997) Intra-amygdala infusion of 2-chloroadenosine suppresses amygdala-kindled seizures. Brain Res. 775 37. PMID: 9439826. Mathotet al (1996) Pharmacokinetic-haemodynamic relationships of 2-chloroadenosine at adenosine A1 and A2areceptorsin vivo. Br.J.Pharmacol. 118 369. PMID: 8735640. |