U 104 (10 MG)
货号:
4540/10 基本售价:
1477.2 元 规格:
10 mg
产品信息
概述货号 | 4540/10 |
别名 | 4-[[[(4-Fluorophenyl)amino]carbonyl]amino]-benzesulfonamide |
性能供应商 | Tocris |
生物活性 | Potent carbonic anhydrase (CA) inhibitor (Ki values are 4.5, 45.1, 5080 and 9640 nM for CA XII, CA IX, CA I and CA II respectively in MDA-MB-231 cells). Inhibits tumor metastasis in the rat 4T1 metastasis model. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 309.32 |
分子式 | C13H12FN3O3< |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
参考文献 | Louet al (2011) Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors. Cancer Res. 71 3364. PMID: 21415165. |