Stattic
货号:
2625-5 基本售价:
1340.0 元 规格:
5mg
产品信息
概述货号 | 2625-5 |
描述 | Stattic is a small molecule that selectively inhibits STAT3 activation, dimerization, and nuclear translocation by preventing the binding of tyrosine-phosphorylated peptide motifs to the STAT3 SH2 domain (IC₅₀ = 5.1 μM at 37°C). Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. At 10 μM, stattic induces apoptosis in STAT3-dependent breast cancer (MDA-MB-231 and MDA-MB-435S) cell lines. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20 ̊C |
CAS号 | 19983-44-9 |
外观 | Pale yellow solid |