| 货号 | 1479/100 |
| 别名 | (11β,17β)-11-[4-(Dimethylamino)phenyl |
| 供应商 | Tocris |
| 生物活性 | Selective antagonist at progesterone (PR) and glucocorticoid (GR) receptors in vitroandin vivo. Is a silent antagonist at PR and has a higher affinity than progesterone. Has higher affinity for GR than dexamethasone (Cat. No. 1126). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 429.6 |
| 分子式 | C29H35NO2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol with gentle warming |
| CAS号 | 84371-65-3 |
| 参考文献 | Maoet al (1992) Molecular mechanism of RU 486 action: a review. Mol.Cell.Biochem. 109 1. PMID: 1614417. Gagneet al (1985) RU 38486: a potent antiglucocorticoid in vitroandin vivo. J.Steroid Biochem. 23 247. PMID: 2864478. Schrieberet al (1983) Binding of the anti-progestin RU 486 to rat ovary steroid receptors. Contraception 28 77. PMID: 6627946. |