货号 | 5858/50 |
别名 | 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl |
供应商 | Tocris |
生物活性 | D2 receptor antagonist. Also exhibits affinity for 5-HT, α-adrenergic and histamine receptors,and hERG channels. Antipsychotic and antiemetic. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 379.43 |
分子式 | C22H22FN3O2< |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
参考文献 | Rajamaniet al (2005) A two-state homology model of the hERG K+ channel: application to ligand binding. Bioorg.Med.Chem.Lett. 15 1737. PMID: 15745831. Peroutka and Synder (1980) Relationship of neuroleptic drug effects at brain dopamine, serotonin, alpha-adrenergic, and histamine receptors to clinical potency. Am.J.Psychiatry 137 1518. PMID: 6108081. |