MS-1020
货号：
14273-1mg 基本售价：
1125.0 元 规格：
1 mg
产品信息
概述| 货号 | 14273-1mg |
| 描述 | MS-1020 is a cell-permeable inhibitor of janus kinase 3 (JAK3), strongly inhibiting constitutive autophosphorylation of JAK3 in L540 cells when used at 30-50 μM.1 It is without effect on other JAK isoforms and several other kinases, including Src, Lyn, Akt, EGFR, and ERK1/2. Through its effects on JAK3, MS-1020 blocks phosphorylation of downstream signal transduction and activators of transcription isoforms, reducing the expression of anti-apoptotic genes, leading to cell death.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kim, B.H.,Oh, S.R.,Yin, C.H., et al. MS-1020 is a novel small molecule that selectively inhibits JAK3 activity. British Journal of Haematology 148(1), 132-143 (2010).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 346.4 |
| 分子式 | C21H18N2O3 |
| CAS号 | 1255516-86-9 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
