| 货号 | 2206/10 |
| 别名 | 2-Hydroxy-1-(hydroxymethyl)ethyl hexadecanoic acid ester |
| 供应商 | Tocris |
| 生物活性 | Endogenous fatty acid glycerol ester that enhances activity of 2-arachidonylglycerol (Cat. No. 1298). Does not bind to CB1 or CB2 cannabinoid receptors, but potentiates the apparent binding of 2-AG and increases its ability to inhibit adenylyl cyclase. Enhances in vivo cannabinoid effects of 2-AG following combined administration with 2-linoleoylglycerol. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 330.51 |
| 分子式 | C19H38O4 |
| 可溶性/溶解性 | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
| CAS号 | 23470-00-0 |
| 参考文献 | Walkeret al (2002) Endocannabinoids and related fatty acid derivatives in pain modulation. Chem.Phys.Lipids 121 159. PMID: 12505698. Gallilyet al (2000) 2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-α production in murine macrophages, and in mice. Eur.J.Pharmacol. 406 R5. PMID: 11011050. Ben-Shabatet al (1998) An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonyl-glycerol cannabinoid activity. Eur.J.Pharmacol. 353 23. PMID: 9721036. |