Sp-Cyclic AMPS (sodium salt)
货号：
14983-1mg 基本售价：
770.0 元 规格：
1 mg
产品信息
概述| 货号 | 14983-1mg |
| 描述 | Several cyclic nucleotide phosphodiesterases (PDE2, -5, -6, -10, and -11) contain a tandem of GAF domains in their N-terminal regulatory region that are thought to mediate cAMP- or cGMP-induced stimulation of adenylyl and guanylyl cyclases.1 Sp-cyclic AMPS (Sp-cAMPS) is a derivative of cAMP that binds the PDE10 GAF domain (EC50 = 40 μM).1 It has been used to study GAF-mediated stimulation of PDE10.1 |
| 别名 | Sp-cAMPS; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Jäger, R.,Russwurm, C.,Schwede, F., et al. Activation of PDE10 and PDE11 phosphodiesterases. The Journal of Biological Chemisty 287(2), 1210-1219 (2012).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 367.3 |
| 分子式 | C10H11N5O5PS • Na |
| CAS号 | 142439-95-0 |
| 稳定性 | ≥ 2 years |
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