2,3-dinor Prostaglandin E1
货号：
13120-25ug 基本售价：
630.0 元 规格：
25 ug
产品信息
概述| 货号 | 13120-25ug |
| 描述 | Prostaglandin E1(PGE1) is not a major naturally occurring prostaglandin, but it is widely administered clinically for several indications including peripheral occlusive vascular disease, erectile dysfunction and in neonatal cardiology.1,2 The metabolism of PGE1 is normally initiated by oxidation at C-15, resulting in 13,14-dihydro-15-keto PGE1 as the major metabolite. However, inhibition of this pathway or saturation by excess substrate could theoretically lead to enhanced production of 2,3-dinor metabolites, including 2,3-dinor PGE1. The biological activity of 2,3-dinor PGE1 has not been published. Cayman Chemical is a leading supplier of prostaglandins and their metabolites, and is currently the exclusive manufacturer of 2,3-dinor PGE1. |
| 别名 | 2,3-dinor PGE1; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Virag, R.,Shoukry, K.,Floresco, J., et al. Intracavernous self-injection of vasoactive drugs in the treatment of impotence: 8-Year experience with 615 cases. Journal of Urology 145, 287-293 (1991).
2.Hoshi, K. Approved indications of lipo-PGE1 in Japan. Advanced Drug Delivery Reviews 20, 171-176 (1996).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 326.4 |
| 分子式 | C18H30O5 |
| CAS号 | 7046-40-4 |
| 稳定性 | ≥ 2 years |
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