10,11-dihydro-10-hydroxy Carbamazepine
货号：
18467-5mg 基本售价：
560.0 元 规格：
5 mg
产品信息
概述| 货号 | 18467-5mg |
| 描述 | 10,11-dihydro-10-hydroxy Carbamazepinee is the active metabolite of oxcarbazepine (Item No. 17340). Oxcarbazepine is rapidly and almost completely converted to 10,11-dihydro-10-hydroxycarbamazepine, which then demonstrates anticonvulsant efficacy by modulating several ion channels and receptors.1,2 10,11-dihydro-10-hydroxy Carbamazepine is reported to inhibit both voltage-gated Na+ and Ca2+ channels, to potentiate voltage-gated K+ channels, to antagonize adenosine A1 receptors, to increase dopaminergic transmission, and to inhibit glutamate release.1 |
| 别名 | BIA 2-005;10,11-hydroxy-10,11 Dihydrocarbamezer;GP 47779;Licarbazepine; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ambrósio, A.F.,Soares-Da-Silva, P.,Carvalho, C.M., et al. Mechanisms of action of carbamazepine and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024. Neurochemical Research 27(1-2), 121-130 (2002).
2.Macdonald, R.L., and Kelly, K.M. Antiepileptic drug mechanisms of action. Epilepsia 36(Suppl 2), S2-S12 (1995).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 254.3 |
| 分子式 | C15H14N2O2 |
| CAS号 | 29331-92-8 |
| 稳定性 | ≥ 2 years |
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