Raltegravir (potassium salt)
货号：
16071-1mg 基本售价：
546.0 元 规格：
1 mg
产品信息
概述| 货号 | 16071-1mg |
| 描述 | Raltegravir is a potent, selective, and orally bioavailable inhibitor of HIV integrase (IC50 = 15 nM).1 It is metabolized primarily by uridine diphosphate glucuronosyltransferase 1A1.2 Raltegravir has long-term efficacy and safety in managing HIV-1 infection in adults, children, and adolescents.2,3 |
| 别名 | MK-0518; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Summa, V.,Petrocchi, A.,Bonelli, F., et al. Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection. Journal of Medicinal Chemistry 1(18), 5843-5855 (2008).
2.Liedtke, M.D.,Tomlin, C.R.,Lockhart, S.M., et al. Long-term efficacy and safety of raltegravir in the management of HIV infection. Infect.Drug Resist. 7, 73-84 (2014).
3.Larson, K.B.,King, J.R. and Acosta, E.P. Raltegravir for HIV-1 infected children and adolescents: Efficacy, safety, and pharmacokinetics. Adolesc.Health Med.Ther. 4, 79-87 (2013).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 482.5 |
| 分子式 | C20H20FN6O5 • K |
| CAS号 | 871038-72-1 |
| 稳定性 | ≥ 2 years |
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