(±)-Salsolinol (hydrochloride)
货号:
15597-100mg 基本售价:
546.0 元 规格:
100 mg
产品信息
概述货号 | 15597-100mg |
描述 | (±)-Salsolinol is a metabolite of ethanol produced by the condensation of dopamine with acetaldehyde in the brain. It is thought to contribute to some aspects of alcohol’s addictive properties in part through its ability to stimulate dopamineric neurons in the posterior ventral tegmental area of the brain.1 At 0.1 μM, (±)-salsolinol has been shown to: a) depolarize dopamineric neurons, which increases their firing rate; b) activate μ-opioid receptors on GABAergic neurons, which disinhibits dopamineric neurons; and c) activate dopamine1-like receptors, which enhances pre-synaptic glutamate transmission to dopamineric neurons.1 |
性能供应商 | Cayman |
应用文献 |
1.Xie, G.,Krnjevic, K. and Ye, J.H. Salsolinol modulation of dopamine neurons. Front.Behav.Neurosci. 7(52), (2013).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | 4 |
纯度 | ≥99% |
计算分子量 | 215.7 |
分子式 | C10H13NO2 • HCl |
CAS号 | 79923-51-6 |
稳定性 | ≥ 1 year |
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