Dexmedetomidine (hydrochloride)
货号：
15581-5mg 基本售价：
546.0 元 规格：
5 mg
产品信息
概述| 货号 | 15581-5mg |
| 描述 | Dexmedetomidine is the (S)-enantiomer of medetomidine, an imidazole compound that binds to α2-adrenoceptors (Ki = 1.08 nM) with high affinity and selectivity compared to that of α1-adrenoceptors (Ki = 1.8 μM).1 Dexmedetomidine produces analgesic, sedative, and anxiolytic effects through both presynaptic activation of α2-adrenoceptors, which inhibits norepinephrine release, and postsynaptic activation of α2-adrenoceptors, which inhibits sympathetic activity and decreases blood pressure and heart rate.2,3 |
| 别名 | Dex;Precedex; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Virtanen, R.,Savola, J.M.,Saano, V., et al. Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonist. European Journal of Pharmacology 150(1-2), 9-14 (1988).
2.Gertler, R.,Brown, H.C.,Mitchell, C.H., et al. Dexmedetomidine: A novel sedative-analgesic agent. Proc.(Bayl.Univ.Med.Cent.) 14(1), 13-21 (2001).
3.Bajwa, S. and Kulshrestha, A. Dexmedetomidine: An adjuvant making large inroads into clinical practice. Ann.Med.Health Sci.Res. 3(4), 475-483 (2013).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥99% |
| 计算分子量 | 236.7 |
| 分子式 | C13H16N2 • HCl |
| CAS号 | 145108-58-3 |
| 稳定性 | ≥ 2 years |
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