5-Octyl L-glutamate
货号：
16107-1mg 基本售价：
532.0 元 规格：
1 mg
产品信息
概述| 货号 | 16107-1mg |
| 描述 | While extracellular glutamic acid is an excitatory neurotransmitter, intracellular glutamic acid is an amino acid that serves numerous metabolic roles, including as a precursor for α-ketoglutarate.1 5-Octyl L-glutamate, also known as 5-octyl ester glutamic acid, is a stable, cell-permeable molecule which generates free glutamic acid upon hydrolysis of the ester bond by cytoplasmic esterases. It may be used in experiments to increase levels of cytoplasmic glutamic acid. Alternatively, 5-octyl L-glutamate can be used to synthesize 5-octyl ester derivatives, including 5-octyl α-ketoglutarate, for delivery to cells.2 |
| 别名 | NSC 522645;5-Octyl ester L-glutamic acid; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bräuner-Osborne, H.,Egebjerg, J.,Nielsen, E.O., et al. Ligands for glutamate receptors: Design and therapeutic prospects. J. Med. Chem. 43(14), 2609-2645 (2000).
2.Chin, R.M.,Fu, X.,Pai, M.Y., et al. The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature 509(7505), 397-401 (2014).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 259.4 |
| 分子式 | C13H25NO4 |
| CAS号 | 4852-91-9 |
| 稳定性 | ≥ 2 years |
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