Ac-IETD-AFC
货号：
17480-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 17480-1mg |
| 描述 | Ac-IETD-AFC is a fluorogenic substrate that can be cleaved by caspase-8 and related enzymes that recognize the amino acid sequence IETD, including caspase-3 processing enzyme, caspase-10, and granzyme B.1 Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. |
| 别名 | N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Reszka, P.,Schulz, R.,Methling, K., et al. Synthesis, enzymatic evaluation, and docking studies of fluorogenic caspase 8 tetrapeptide substrates. ChemMedChem 5, 103-117 (2010).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 729.7 |
| 分子式 | C31H38F3N5O12 |
| CAS号 | 211990-57-7 |
| 稳定性 | ≥ 2 years |
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