Bosentan
货号：
11731-5mg 基本售价：
490.0 元 规格：
5 mg
产品信息
概述| 货号 | 11731-5mg |
| 描述 | Bosentan is an antagonist of the endothelin receptors type A (Ki = 6.5 nM) and type B (Ki = 340 nM).1,2 |
| 别名 | Ro 47-0203; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Jae, H.S.,Winn, M.,Dixon, D.B., et al. Pyrrolidine-3-carboxylic acids as endothelin antagonists. 2. Sulfonamide-based ETA/ETB mixed antagonists. J. Med. Chem. 40(20), 3217-3227 (1997).
2.Wu, C.,Decker, E.R.,Blok, H., et al. Discovery, modeling, and human pharmacokinetics of N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)-thiophene-2-carboxamide (TBC3711), a second generation, ETA selective, and orally bioavailable endothelin antagonist. J. Med. Chem. 47(8), 1969-1986 (2004).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 551.6 |
| 分子式 | C27H29N5O6S |
| CAS号 | 147536-97-8 |
| 稳定性 | ≥ 2 years |
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