| 货号 | 19649-1mg |
| 描述 | D,L-1′-Acetoxychavicol acetate is a natural compound first isolated from the rhizomes of ginger-like plants. It has a wide array of cellular effects that may be largely explained by its ability to inhibit exportin 1 and prevent the export of proteins from the nucleus.1,2 In this way, D,L-1′-acetoxychavicol acetate reduces several intracellular signaling pathways, including NF-κB, impacting inflammation, cancer, viral replication, and other processes.3,2,4 |
| 别名 | ACA;1-Acetoxychavicol Acetate;Galangal Acetate; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Tamura, S.,Shiomi, A.,Kaneko, M., et al. New rev-export inhibitor from Alpinia galanga and structure-activity relationship. Bioorganic & Medicinal Chemistry Letters 19(9), 2555-2557 (2009). 2.Turner, J.G.,Dawson, J. and Sullivan, D.M. Nuclear export of proteins and drug resistance in cancer. Biochemical Pharmacology 83(8), 1021-1032 (2012). 3.Murakami, A. and Ohigashi, H. Targeting NOX, INOS and COX-2 in inflammatory cells: Chemoprevention using food phytochemicals. International Journal of Cancer 121(11), 2357-2363 (2007). 4.Watanabe, K.,Takatsuki, H.,Sonoda, M., et al. Anti-influenza viral effects of novel nuclear export inhibitors from Valerianae Radix and Alpinia galanga. Drug Discov.Ther. 5(1), 26-31 (2016). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 234.3 |
| 分子式 | C13H14O4 |
| CAS号 | 52946-22-2 |
| 稳定性 | ≥ 2 years |
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