Apoptosis Activator 2
货号：
10004176-5mg 基本售价：
392.0 元 规格：
5 mg
产品信息
概述| 货号 | 10004176-5mg |
| 描述 | Apoptosis activator 2 promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome, thus increasing procaspase-9 processing and subsequent caspase-3 activation.1 This compound has been shown to induce apoptosis in leukemia cells (IC50 = 4-9 μM) with weak or no effect on normal cell lines or those lacking Apaf-1, caspase-9, or caspase-3 activity (IC50s > 40 μM).1 |
| 别名 | AAII;N-(3,4-dichlorobenzyl) Isatin; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Nguyen, J.T., and Wells, J.A. Direct activation of the apoptosis machinery as a mechanism to target cancer cells. Proceedings of the National Academy of Sciences of the United States of America 100(13), 7533-7538 (2003).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 306.1 |
| 分子式 | C15H9Cl2NO2 |
| CAS号 | 79183-19-0 |
| 稳定性 | ≥ 2 years |
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