| 货号 | 14985-10mg |
| 描述 | Clenbuterol is a sympathomimetic β2-adrenoceptor agonist that has been used as a bronchodilator (20 μg per dose in humans) in the treatment of pulmonary diseases such as asthma.1,2 At higher doses (2 mg/kg/day in rats), clenbuterol acts as an anabolic steroid, favoring skeletal muscle protein synthesis at the expense of fat deposition.3 Because of this property, clenbuterol has been illegally used by athletes to enhance performance, by dieters to encourage weight loss, and by livestock farmers to produce animals with leaner meat.4,5 The use of clenbuterol is banned by the U.S. Food and Drug Administration as well as the International Olympic Committee and is prohibited for use in food-producing animals in the U.S., the European Union, and China.6 Clenbuterol can also produce relaxation of smooth muscle in the uterus and has been used in the short-term postponement of parturition in veterinary obstetrical procedures.7 |
| 别名 | NAB 365;Ventipulmin; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kamburoff, P.L.,Prime, F.J. and Schmidt, O.P. The bronchodilator effect of NAB 365. British Journal of Clinical Pharmacology 4(1), 67-71 (1977). 2.Anderson, G. and Wilkins, E. A trial of clenbuterol in bronchial asthma. Thorax 32(6), 717-719 (1977). 3.Rothwell, N.J.,Stock, M.J. and Sudera, D.K. Changes in tissue blood flow and β-receptor density of skeletal muscle in rats treated with the β2-adrenoceptor agonist clenbuterol. British Journal of Pharmacology 90(3), 601-607 (1987). 4.Thein, L.A.,Thein, J.M. and Landry, G.L. Ergogenic aids. Phys.Ther. 75(5), 426-439 (1995). 5.Mitchell, G.A. and Dunnavan, G. Illegal use ofβadrenergic agonists in the United States. Journal of Animal Science 76(1), 208-211 (1998). 6.Cai, J. and Henion, J. Quantitative multi-residue determination of β-agonists in bovine urine using on-line immunoaffinity extraction-coupled column packed capillary liquid chromatography-tandem mass spectrometry. Journal of Chromatography B 691, 357-370 (1997). 7.Denooij, P.P. The use of clenbuterol for obstetrical procedures in forty cows and one horse. Can.Vet.J. 25(9), 357-359 (2013). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 313.7 |
| 分子式 | C12H18Cl2N2O • HCl |
| CAS号 | 21898-19-1 |
| 稳定性 | ≥ 2 years |
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