N6022
货号：
21269-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 21269-1mg |
| 描述 | N6022 is a tight-binding, specific, and fully reversible inhibitor of S-nitrosoglutathione reductase (GSNOR; IC50 = 8 nM; Ki = 2.5 nM).1 It is reported to bind in the GSNO substrate binding pocket like a competitive inhibitor, although in kinetic assays it behaves with a mixed uncompetitive mode of inhibition toward the GSNO substrate and a mixed competitive mode of inhibition toward the formaldehyde adduct, S-hydroxymethylglutathione.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Green, L.S.,Chun, L.E.,Patton, A.K., et al. Mechanism of inhibition for N6022, a first-in-class drug targeting S-nitrosoglutathione reductase. Biochemistry 51(10), 2157-2168 (2012).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 414.5 |
| 分子式 | C24H22N4O3 |
| CAS号 | 1208315-24-5 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
