| 货号 | 21001-5g |
| 描述 | Cinnarizine is a piperazine derivative that has diverse cellular and physiological actions. It is a histamine (H) receptor antagonist (Ki = 142 nM for H4) and calcium channel blocker that potently dilates peripheral vessels.1,2,3 Formulations containing cinnarizine have been used to manage vertigo, nausea, and migraines.2,4 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Singh, B.N. The mechanism of action of calcium antagonists relative to their clinical applications. Br. J. Clin. Pharmacol. 21, 109S-121S (1986). 2.Soto, E. and Vega, R. Neuropharmacology of vestibular system disorders. Curr. Neuropharmacol. 8(1), 26-40 (2010). 3.Nguyen, T.,Shapiro, D.A.,George, S.R., et al. Discovery of a novel member of the histamine receptor family. Mol. Pharmacol. 59(3), 427-433 (2001). 4.Raghuvanshi, S. and Pathak, K. Recent advances in delivery systems and therapeutics of cinnarizine: A poorly water soluble drug with absorption window in stomach. J. Drug. Deliv. 2014, 479246 (2014). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥98% |
| 计算分子量 | 368.5 |
| 分子式 | C26H28N2 |
| CAS号 | 298-57-7 |
| 稳定性 | ≥ 2 years |
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