Selonsertib
货号：
20972-500ug 基本售价：
350.0 元 规格：
500 ug
产品信息
概述| 货号 | 20972-500ug |
| 描述 | Selonsertib is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1; IC50 = 3.2 nM), which is involved in a variety of conditions, including fibrosis, oxidative stress, and inflammation, among others.1 A formulation containing selonsertib showed antifibrotic activity in a Phase II clinical trial. Clinical trials are ongoing for other conditions, including severe alcoholic hepatitis and nonalcoholic steatohepatitis. |
| 别名 | GS 4997; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Notte, G. Apoptosis signal-regulating kinase inhibitors. (2013).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 445.5 |
| 分子式 | C24H24FN7O |
| CAS号 | 1448428-04-3 |
| 稳定性 | ≥ 2 years |
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