Benserazide (hydrochloride)
货号：
20298-500mg 基本售价：
350.0 元 规格：
500 mg
产品信息
概述| 货号 | 20298-500mg |
| 描述 | Benserazide is an inhibitor of aromatic L-amino acid decarboxylase (AADC), an enzyme that has dopamine decarboxylase activity.1,2 It is also unable to cross the blood-brain barrier. As a result, benserazide blocks the conversion of L-DOPA (Item No. 13248) to dopamine by AADC in the peripheral circulatory system. Benserazide is often combined with L-DOPA in patients with Parkinson’s disease.3 |
| 别名 | Ro 4-4602; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Shen, H.,Kannari, K.,Yamato, H., et al. Effects of benserazide on L-DOPA-derived extracellular dopamine levels and aromatic L-amino acid decarboxylase activity in the striatum of 6-hydroxydopamine-lesioned rats. Tohoku J.Exp.Med. 199(3), 149-159 (2003).
2.Soares-Da-Silva, P.,Serrão, M.P., and Vieira-Coelho, M.A. Apical and basolateral uptake and intracellular fate of dopamine precursor L-dopa in LLC-PK1 cells. Am.J.Physiol. 274(2 Pt 2), F243-251 (1998).
3.Di Stefano, A.,Dozio, P., and Cerasa, L.S. Antiparkinson prodrugs. Molecules 13(1), 46-68 (2008).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 293.7 |
| 分子式 | C10H15N3O5 • HCl |
| CAS号 | 14919-77-8 |
| 稳定性 | ≥ 2 years |
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