| 货号 | 19765-1g |
| 描述 | Morin is a natural pentahydroxyflavonol with antioxidant activity.1 It reduces CD36 expression and oxLDL uptake in U937-derived macrophages, inhibits PIM-1 kinase in vitro(IC50 = 2.7 µM), and reduces the activity of cytochrome P450 isoform 3A4 in liver microsomes.2,3,4 Through these and other actions, morin has anti-oxidant, anti-inflammatory, and other actions in animal models.5 |
| 别名 | Aluminum Ionophore I;LDN-0058388;LY 002079;NSC 19801;2,3,4,5,7-Pentahydroxyflavone; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Duthie, G., and Morrice, P. Antioxidant capacity of flavonoids in hepatic microsomes is not reflected by antioxidant effects in vivo. Oxid.Med.Cell.Longev. 2012, 1-7 (2012). 2.Lian, T.-W.,Wang, L.,Lo, Y.-H., et al. Fisetin, morin and myricetin attenuate CD36 expression and oxLDL uptake in U937-derived macrophages. Biochimica et Biophysica Acta 1781, 601-609 (2008). 3.Holder, S.,Zemskova, M.,Zhang, C., et al. Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase. Molecular Cancer Therapeutics 6(1), 163-172 (2007). 4.Ho, P.C., and Saville, D.J. Inhibition of human CYP3A4 activity by grapefruit flavonoids, furanocoumarins and related compounds. Journal of Pharmacy & Pharmaceutical Sciences 4(3), 217-227 (2001). 5.Spiteller, G. Furan fatty acids: occurrence, synthesis, and reactions. Are furan fatty acids responsible for the cardioprotective effects of a fish diet. Lipids 40(8), 775-771 (2005). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 302.2 |
| 分子式 | C15H10O7 |
| CAS号 | 480-16-0 |
| 稳定性 | ≥ 2 years |
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