Bizine
货号：
19705-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 19705-1mg |
| 描述 | Bizine is a phenelzine analog that inhibits lysine-specific demethylase 1 (LSD1; Ki(inact) = 59 nM).1 It is 23-fold, 63-fold, and >100-fold selective for LSD-1 over monoamine oxidase (MAO) A, MAOB, and LSD2, respectively.1 Bizine has been shown to induce bulk histone H3 lysine 4 dimethylation in LNCaP cancer cells (EC50 = ~2 µM) and, at 0.5 µM, to protect neurons exposed to oxidative stress.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Prusevich, P.,Kalin, J.H.,Ming, S.A., et al. A selective phenelzine analogue inhibitor of histone demethylase LSD1. ACS Chem Biol. 9, 1284-1293 (2014).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 297.4 |
| 分子式 | C18H23N3O |
| CAS号 | 1591932-50-1 |
| 稳定性 | ≥ 2 years |
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