D-Saccharic Acid 1,4-lactone (hydrate)
货号：
18896-100mg 基本售价：
350.0 元 规格：
100 mg
产品信息
概述| 货号 | 18896-100mg |
| 描述 | D-Saccharic acid 1,4-lactone is an inhibitor of β-glucuronidase (IC50 = 45 µM for the human enzyme).1 It is commonly used as a standard in the development of novel inhibitors of β-glucuronidase.1,2 D-Saccharic Acid 1,4-lactone is also used to prevent the cleavage of glucuronides in plasma, serum, or urine by β-glucuronidase in samples.3 |
| 别名 | D-Glucaro-1,4-lactone; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Khan, K.M.,Saad, S.M.,Shaikh, N.N., et al. Synthesis and β-glucuronidase inhibitory activity of 2-arylquinazolin-4(3H)-ones. Bioorganic & Medicinal Chemistry 22(13), 3449-3454 (2014).
2.Jamil, W.,Perveen, S.,Shah, S.A.A., et al. Phenoxyacetohydrazide Schiff bases: β-Glucuronidase inhibitors. Molecules 19(7), 8788-8802 (2014).
3.Lu, Q.Y.,Zhang, L.,Eibl, G., et al. Overestimation of flavonoid aglycones as a result of the ex vivo deconjugation of glucuronides by the tissue β-glucuronidase. Journal of Pharmaceutical & Biomedical Analysis 88, 364-369 (2014).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 210.1 |
| 分子式 | C6H8O7 • H2O |
| CAS号 | 61278-30-6 |
| 稳定性 | ≥ 2 years |
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