UBP 301
货号:
17597-1mg 基本售价:
350.0 元 规格:
1 mg
产品信息
概述货号 | 17597-1mg |
描述 | UBP 301 is an antagonist of the kainate receptor, an ionotropic glutamate receptor (apparent Kd = 5.94 µM).1 It displays ~30-fold selectivity over AMPA receptors.1 UBP 301 is used to assess the roles of kainate receptors in neuronal signaling, particularly in reference to neuropathic pain.2,3 |
性能供应商 | Cayman |
应用文献 |
1.More, J.C.A.,Troop, H.M.,Dolman, N.P., et al. Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists. British Journal of Pharmacology 138(6), 1093-1100 (2003). 2.Doolen, S.,Blake, C.B.,Smith, B.N., et al. Peripheral nerve injury increases glutamate-evoked calcium mobilization in adult spinal cord neurons. Molecular Pain 8, 1-12 (2012). 3.Osgood, D.B.,Harrington, W.F.,Kenney, E.V., et al. The utility of ionotropic glutamate receptor antagonists in the treatment of nociception induced by epidural glutamate infusion in rats. Surg.Neurol.Int. 4, 1-9 (2013).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 459.2 |
分子式 | C15H14IN3O6 |
CAS号 | 569371-10-4 |
稳定性 | ≥ 2 years |
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