| 货号 | 17592-1mg |
| 描述 | L-Deoxyalliin (Item No. 14014), also known as S-allyl-L-cysteine, is a water soluble organosulfur compound derived from garlic that has neuroprotective and antioxidative activities.1,2 N-Acetyl-S-allyl-L-cysteine is a principal metabolite of L-deoxyalliin in humans, mice, rats, and dogs.3,4,5 It is readily detected in plasma and urine. The conversion of L-deoxyalliin to N-acetyl-S-allyl-L-cysteine appears to be mediated by a family of flavin-containing monooxygenases.4,6 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kim, J.M.,Chang, H.J.,Kim, W.K., et al. Structure-activity relationship of neuroprotective and reactive oxygen species scavenging activities for allium organosulfur compounds. Journal of Agricultural and Food Chemistry 54, 6547-6553 (2006). 2.Colín-González, A.L.,Santana, R.A.,Silva-Islas, C.A., et al. The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection. Oxid.Med.Cell Longev. 2012, (2012). 3.de Rooij, B.M.,Boogaard, P.J.,Rijksen, D.A., et al. Urinary excretion of N-acetyl-S-allyl-L-cysteine upon garlic consumption by human volunteers. Archives of Toxicology 70(10), 635-639 (1996). 4.Krause, R.J.,Glocke, S.C., and Elfarra, A.A. Sulfoxides as urinary metabolites of S-allyl-L-cysteine in rats: Evidence for the involvement of flavin-containing monooxygenases. Drug Metabolism and Disposition 30(10), 1137-1142 (2002). 5.Amano, H.,Kazamori, D.,Itoh, K., et al. Metabolism, excretion, and pharmacokinetics of S-allyl-l-cysteine in rats and dogs. Drug Metabolism and Disposition 43(5), 749-755 (2015). 6.Krause, R.J.,Lash, L.H., and Elfarra, A.A. Human kidney flavin-containing monooxygenases and their potential roles in cysteine S-conjugate metabolism and nephrotoxicity. Journal of Pharmacology and Experimental Therapeutics 304(1), 185-191 (2003). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 203.3 |
| 分子式 | C8H13NO3S |
| CAS号 | 23127-41-5 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |