Ac-YVAD-AFC
货号:
17591-1mg 基本售价:
350.0 元 规格:
1 mg
产品信息
概述货号 | 17591-1mg |
描述 | Ac-YVAD-AFC is a substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4.1,2 Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. |
别名 | Caspase-1 Substrate VI (Fluorogenic);Ac-Tyr-Val-Ala-Asp-7-amido-4-Trifluoromethlcoumarin; |
性能供应商 | Cayman |
应用文献 |
1.Talanian, R.V.,Quinlan, C.,Trautz, S., et al. Substrate specificities of caspase family proteases. The Journal of Biological Chemisty 272, 9677-9682 (1997). 2.Marcelli, M.,Cunningham, G.R.,Haidacher, S.J., et al. Caspase-7 is activated during lovastatin-induced apoptosis of the prostate cancer cell line LNCaP. Cancer Research 58(1), 76-83 (1998).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 719.7 |
分子式 | C33H36F3N5O10 |
CAS号 | 219137-85-6 |
稳定性 | ≥ 2 years |
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