Ifosfamide
货号：
17562-50mg 基本售价：
350.0 元 规格：
50 mg
产品信息
概述| 货号 | 17562-50mg |
| 描述 | Ifosfamide is a nitrogen mustard alkylating agent used as a chemotherapeutic agent against advanced transitional cell carcinoma.1 It is a structural derivative of cyclophosphamide (Item No. 13849) that was developed for improved solubility and antitumor activity. Like cyclophosphamide, ifosfamide serves as a prodrug that is either metabolized to its active DNA alkylating form, isophosphoramide mustard, or catabolized through a dechloroethylation pathway to the neurotoxic and nephrotoxic chloroacetaldehyde.2 |
| 别名 | Isophosphamide;NSC 109724; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Perabo, F.G.E., and Müller, S.C. New agents for treatment of advanced transitional cell carcinoma. Annals of Oncology 18, 835-843 (2007).
2.Tascilar, M.,Loos, W.J.,Seynaeve, C., et al. The pharmacologic basis of ifosfamide use in adult patients with advanced soft tissue sarcomas. Oncologist 12, 1351-1360 (2007).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 261.1 |
| 分子式 | C7H15Cl2N2O2P |
| CAS号 | 3778-73-2 |
| 稳定性 | ≥ 2 years |
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