| 货号 | 17561-50mg |
| 描述 | Tianeptine is an atypical antidepressant with diverse actions, most notably on the glutamatergic system.1,2 It attenuates glutamate release and modulates the function of the AMPA receptor.2,3 Tianeptine also acts as an agonist of the µ-opioid receptor (EC50s = 194 and 641 nM for human and mouse receptors, respectively).4 It is as effective as fluoxetine (Item No. 14418) in the management of post-traumatic stress disorder.5 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Wagstaff, A.J.,Ormrod, D., and Spencer, C.M. Tianeptine: A review of its use in depressive disorders. CNS Drugs 15(3), 231-259 (2001). 2.McEwen, B.S.,Chattarji, S.,Diamond, D.M., et al. The neurobiological properties of Tianeptine (Stablon): From monoamine hypothesis to glutamatergic modulation. Molecular Psychiatry 15(3), 237-249 (2010). 3.Zhang, H.,Etherington, L.A.,Hafner, A.S., et al. Regulation of AMPA receptor surface trafficking and synaptic plasticity by a cognitive enhancer and antidepressant molecule. Molecular Psychiatry 18, 471-484 (2013). 4.Gassaway, M.M.,Rives, M.L.,Kruegel, A.C., et al. The atypical antidepressant and neurorestorative agent tianeptine is a μ-opioid receptor agonist. Transl.Psychiatry 4, 1-5 (2014). 5.Franciskovic, T.,Sukovic, Z.,Janovic, S., et al. Tianeptine in the combined treatment of combat related posttraumatic stress disorder. Psychiatria Danubina 23(3), 257-263 (2011). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 458.9 |
| 分子式 | C21H24ClN2O4S • Na |
| CAS号 | 30123-17-2 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |