Nourseothricin (sulfate)
货号：
16227-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 16227-1mg |
| 描述 | Nourseothricin is a broad-spectrum antibiotic produced by Streptomyces variants that inhibits protein synthesis by inducing miscoding. It is commonly used as a dominant selection antibiotic for genetically modified bacteria, yeasts, fungi, protozoa, plants, and mammalian cells.1,2 Selection of recombinant strains is based on inactivation of nourseothricin by acetylation of the β-amino group of the β-lysine by nourseothricin N-acetyltransferase.3 |
| 别名 | clonNAT;Streptothricin; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Shen, J.,Guo, W. and Köhler, J.R. CaNAT1, a heterologous dominant selectable marker for transformation of Candida albicans and other pathogenic Candida species. Infection and Immunity 73(2), 1239-1242 (2005).
2.Kochupurakkal, B.S. and Iglehart, J.D. Nourseothricin N-acetyl transferase: A positive selection marker for mammalian cells. PLoS One 8(7), 1-4 (2013).
3.Grammel, N.,Pankevych, K.,Demydchuk, J., et al. A β-lysine adenylating enzyme and a β-lysine binding protein involved in poly β-lysine chain assembly in nourseothricin synthesis in Streptomyces noursei. European Journal of Biochemistry 269(1), 347-357 (2002).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 计算分子量 | 1359.5 |
| 分子式 | C31H58N12O10 • C19H34N8O8 • H2SO4 |
| CAS号 | 96736-11-7 |
| 稳定性 | ≥ 2 years |
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