1-O-Octadecyl-2-O-methyl-sn-glycerol
货号：
15108-50mg 基本售价：
350.0 元 规格：
50 mg
产品信息
概述| 货号 | 15108-50mg |
| 描述 | 1-O-Octadecyl-2-O-methyl-sn-glycerol is a metabolite of a phosphotidylinositol ether lipid analog (PIA). PIAs are known to target the pleckstrin homology domain of the serine/threonine kinase Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity.1,2 |
| 别名 | 2-Methyl-1-octadecyl-sn-glycerol;PIA 7; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Castillo, S.S.,Brognard, J.,Petukhov, P.A., et al. Preferential inhibition of Akt and killing of Akt-dependent cancer cells by rationally designed phosphatidylinositol ether lipid analogues. Cancer Research 64(8), 2782-2792 (2004).
2.Memmott, R.M.,Gills, J.J.,Hollingshead, M., et al. Phosphatidylinositol ether lipid analogues induce AMP-activated protein kinase-dependent death in LKB1-mutant non-small cell lung cancer cells. Cancer Research 68(2), 580-588 (2008).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 358.6 |
| 分子式 | C22H46O3 |
| CAS号 | 83167-59-3 |
| 稳定性 | ≥ 2 years |
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