R-(-)-Deprenyl (hydrochloride)
货号：
15046-100mg 基本售价：
350.0 元 规格：
100 mg
产品信息
概述| 货号 | 15046-100mg |
| 描述 | Monoamine oxidase (MAO) inhibitors have utility in ameliorating a variety of neurological conditions, including depression.1 R-(−)-Deprenyl is a selective, reversible inhibitor of MAO-B (Ki = 0.091 μM) over MAO-A (Ki = 9.06 μM).2,3 In addition to finding use against depression, R-(−)-deprenyl provides neuroprotection which may be relevant to Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and stroke.4,1 The ability of this compound to slow the progression of disability in early Parkinson’s disease may be independent of its effects on MAO activity.4 |
| 别名 | L-Deprenyl;Selegiline; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wimbiscus, M.,Kostenko, O. and Malone, D. MAO inhibitors: Risks, benefits, and lore. Cleveland Clinic Journal of Medicine 77(12), 859-882 (2010).
2.Jagrat, M.,Behera, J.,Yabanoglu, S., et al. Pyrazoline based MAO inhibitors: Synthesis, biological evaluation and SAR studies. Bioorganic & Medicinal Chemistry Letters 21(14), 4296-4300 (2011).
3.La Regina, G.,Silvestri, R.,Gatti, V., et al. Synthesis, structure-activity relationships and molecular modeling studies of new indole inhibitors of monoamine oxidases A and B. Bioorganic & Medicinal Chemistry 16(22), 9729-9740 (2008).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 223.7 |
| 分子式 | C13H17N • HCl |
| CAS号 | 14611-52-0 |
| 稳定性 | ≥ 2 years |
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