UK 383367
货号：
15029-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 15029-1mg |
| 描述 | UK 383367 is a potent inhibitor of bone morphogenetic protein 1 (BMP1; IC50 = 44 nM).1,2 It is more than 200-fold selective for BMP1 over a panel of matrix metalloproteinases. UK 383367 is effective in a cell-based model of collagen deposition is very effective at penetrating human skin in vitro.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Fish, P.V.,Allan, G.A.,Bailey, S., et al. Potent and selective nonpeptidic inhibitors of procollagen C-proteinase. J.Med.Chem. 50915), 3442-3456 (2007).
2.Bailey, S.,Fish, P.V.,Billotte, S., et al. Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically applied, dermal anti-scarring agents. Bioorg.Med.Chem.Lett. 18(24), 6562-6567 (2008).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 324.4 |
| 分子式 | C15H24N4O4 |
| CAS号 | 348622-88-8 |
| 稳定性 | ≥ 2 years |
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