| 货号 | 14979-1mg |
| 描述 | Polygodial is a sesquiterpene dialdehyde isolated from the leaves of certain peppers and related plants. Noted for its broad antifungal properties, polygodial is also cytotoxic against bacteria, algae, and sea squirts.1,2,3 In mammals, polygodial produces a pungent flavor, activates the transient receptor potential cation channel TRPA1 (EC50 = 59 nM), and produces antinociception.4,5 |
| 别名 | Tadeonal; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Lee, S.H.,Lee, J.R.,Lunde, C.S., et al. In vitro antifungal susceptibilities of Candida albicans and other fungal pathogens to polygodial, a sesquiterpene dialdehyde. Planta Medica 65(3), 204-208 (1999). 2.Anke, H. and Sterner, O. Comparison of the antimicrobial and cytotoxic activities of twenty unsaturated sesquiterpene dialdehydes from plants and mushrooms. Planta Medica 57(4), 344-346 (1991). 3.Cahill, P.,Heasman, K.,Jeffs, A., et al. Preventing ascidian fouling in aquaculture: screening selected allelochemicals for anti-metamorphic properties in ascidian larvae. Biofouling 28, 39-49 (2012). 4.Baraldi, P.G.,Preti, D.,Materazzi, S., et al. Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. J. Med. Chem. 53(14), 5085-5107 (2010). 5.Mendes, G.L.,Santos, A.R.S.,Malheiros, A., et al. Assessment of mechanisms involved in antinociception caused by sesquiterpene polygodial. Journal of Pharmacology and Experimental Therapeutics 292(1), 164-172 (2000). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 234.3 |
| 分子式 | C15H22O2 |
| CAS号 | 6754-20-7 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |