| 货号 | 14918-1g |
| 描述 | Spermidine is a natural polyamine produced from putrescine and decarboxylated S-adenosylmethionine (dcSAM) by spermidine synthase. With a second molecule of dcSAM, it is converted to spermine by spermine synthase. Both reactions also produce SAM. Spermidine plays diverse roles in signal transduction and metabolism.1,2,3,4 Polyamines, including spermidine, are involved in growth, development, and stress responses in plants.5 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Nishimura, N.,Takai, M.,Yamamoto, E., et al. Purpurin as a specific inhibitor of spermidine-induced autoactivation of the protease plasma hyaluronan-binding protein. Biological and Pharmaceutical Bullentin 33(8), 1430-1433 (2010). 2.Babbar, N.,Ignatenko, N.A.,Casero, R.A., Jr., et al. Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer. The Journal of Biological Chemisty 278(48), 47762-47775 (2003). 3.Ramot, Y.,Tiede, S.,Bíró, T., et al. Spermidine promotes human hair growth and is a novel modulator of human epithelial stem cell functions. PLoS One 6(7), (2011). 4.Prunotto, M.,Compagnone, A.,Bruschi, M., et al. Endocellular polyamine availability modulates epithelial-to-mesenchymal transtition and unfolded protein response in MDCK cells. Lab Invest. 90(6), 929-939 (2010). 5.Gill, S.S. and Tuteja, N. Polyamines and abiotic stress tolerance in plants. Plant Signal.Behav. 5(1), 26-33 (2010). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 145.3 |
| 分子式 | C7H19N3 |
| CAS号 | 124-20-9 |
| 稳定性 | ≥ 1 year |
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