Src Kinase Inhibitor I
货号：
14592-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 14592-1mg |
| 描述 | The Src kinases constitute a family of non-receptor tyrosine kinases, which includes Src and Lck. Src kinase inhibitor I is a potent competitive inhibitor of both Src and Lck (IC50 = 44 and 88 nM, respectively), as well as Csk and Yes.1,2 It less effectively blocks the receptor tyrosine kinases VEGFR2 and C-fms (IC50 = 0.32 and 30 µM), as well as a long list of serine/threonine kinases.1,2 Src Kinase Inhibitor I also inhibits receptor-interacting protein-2 with an IC50 value of 26 nM.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Tian, G.,Cory, M.,Smith, A.A., et al. Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines. Biochemistry 40(24), 7084-7091 (2001).
2.Bain, J.,Plater, L.,Elliot, M., et al. The selectivity of protein kinase inhibitors: A further update. Biochemistry Journal 408, 297-315 (2007).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 373.4 |
| 分子式 | C22H19N3O3 |
| CAS号 | 179248-59-0 |
| 稳定性 | ≥ 2 years |
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