| 货号 | 11809-1mg |
| 描述 | (−)-Epigallocatechin ((−)-EGC) is a major green tea polyphenol with antioxidant, anti-inflammatory, and anticancer activities. It has been shown to scavenge DPPH radicals with an EC50 value of 0.01 mM and to prevent the growth of several different AML cell lines at micromolar concentrations.1,2,3 Furthermore, at 30 µM (−)-EGC can inhibit heregulin-β1-induced migration/invasion of MCF-7 human breast cancer cells.4 |
| 别名 | (−)-EGC;epi-Gallocatechin;NSC 674039; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Xu, J.Z.,Yeung, S.Y.V.,Chang, Q., et al. Comparison of antioxidant activity and bioavailability of tea epicatechins with their epimers. British Journal of Nutrition 91(6), 873-881 (2004). 2.Kadome, Y., and Fujisawa, S. Radical-scavenging activity of dietary phytophenols in combination with co-antioxidants using the induction period method. Molecules 16, 10457-10470 (2011). 3.Ly, B.T.K.,Chi, H.T.,Yamagishi, M., et al. Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. PLoS One 8(6), 1-9 (2013). 4.Kushima, Y.,Iida, K.,Nagaoka, Y., et al. Inhibitory effect of (−)-epigallocatechin and (−)-epigallocatechin gallate against heregulin β1-induced migration/invasion of the MCF-7 breast carcinoma cell line. Biological and Pharmaceutical Bullentin 32(5), 899-904 (2009). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 306.3 |
| 分子式 | C15H14O7 |
| CAS号 | 970-74-1 |
| 稳定性 | ≥ 2 years |
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