Aflatoxin B1
货号：
11293-1mg 基本售价：
336.0 元 规格：
1 mg
产品信息
概述| 货号 | 11293-1mg |
| 描述 | Aflatoxins are naturally occuring mycotoxins produced by various species of the mold Aspergillus, which can be found in legumes, corn, soybeans, rice, milk, and cheese. They are highly carcinogenic substances that are metabolized by the liver to a reactive epoxide intermediate, which produces adducts that modify DNA. Aflatoxin B1 induces transversion of G to T at codon 249 of the p53 tumor suppressor gene. This transversion is common in hepatocellular carcinoma patients living in regions with high levels of aflatoxin contamination.1 This compound may be used as an internal standard when monitoring foodstuffs for aflatoxin contamination. |
| 别名 | AFB1;HSDB 3453;NSC 529592; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Aguilar, F.,Hussain, S.P., and Cerutti, P. Aflatoxin B1 induces the transversion of G -> T in codon 249 of the p53 tumor suppressor gene in human hepatocytes. Proceedings of the National Academy of Sciences of the United States of America 90, 8586-8590 (1993).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 312.3 |
| 分子式 | C17H12O6 |
| CAS号 | 1162-65-8 |
| 稳定性 | ≥ 2 years |
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