NQTrp
货号：
19127-1mg 基本售价：
266.0 元 规格：
1 mg
产品信息
概述| 货号 | 19127-1mg |
| 描述 | NQTrp is an inhibitor of Alzheimer’s disease-associated amyloid β (Aβ) oligomerization and fibrillization (IC50 = 50 nM for formation of fibrils from Aβ1-42).1,2 It has been shown to reduce the cytotoxic effect of Aβ oligomers in a cultured neuronal cell line.1 |
| 别名 | 1,4-Naphthoquinon-2-yl-L-tryptophan; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Scherzer-Attali, R.,Pellarin, R.,Convertino, M., et al. Complete phenotypic recovery of an Alzheimer’s disease model by a quinone-tryptophan hybrid aggregation inhibitor. PLoS One 5(6), (2010).
2.Zhang, T.,Xu, W.,Mu, Y., et al. Atomic and dynamic insights into the beneficial effect of the 1,4-naphthoquinon-2-yl-L-tryptophan inhibitor on Alzheimer’s Aβ1-42 dimer in terms of aggregation and toxicity. ACS Chem.Neurosci. 5(2), 148-159 (2016).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 360.4 |
| 分子式 | C21H16N2O4 |
| CAS号 | 185351-19-3 |
| 稳定性 | ≥ 2 years |
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