NSC 210902
货号：
10011255-1mg 基本售价：
182.0 元 规格：
1 mg
产品信息
概述| 货号 | 10011255-1mg |
| 描述 | Casein Kinase 2 (CK2) is a serine/threonine-selective protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis, and its activity is increased in many proliferating tissues and tumors, which lends promise as an anticancer drug target. NSC 210902 inhibits CK2 with an IC50 value of 1 µM and competitively inhibits binding of ATP with a Ki value of 0.28 µM.1 NSC 210902 is selective for CK2 as it only minimally inhibits the activities of other protein kinases (e.g., JNK3, GSK3, Cdk5, and MSK1).1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Golub, A.G.,Yakovenko, O.Y.,Bdzhola, V.G., et al. Evaluation of 3-carboxy-4(1H)-quinolones as inhibitors of human protein kinase CK2. Journal of Medicinal Chemistry 49, 6443-6450 (2006).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 239.2 |
| 分子式 | C14H9NO3 |
| CAS号 | 51726-83-1 |
| 稳定性 | ≥ 2 years |
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