PF-750
货号：
10010908-1mg 基本售价：
182.0 元 规格：
1 mg
产品信息
概述| 货号 | 10010908-1mg |
| 描述 | Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. PF-750 is a potent, time-dependent, irreversible FAAH inhibitor with IC50 values of 0.6 and 0.016 µM when preincubated with recombinant human FAAH for 5 and 60 minutes, respectively.1 Activity-based profiling of various human and murine tissue proteome samples revealed that PF-750 is highly selective for FAAH relative to other serine hydrolases, showing no discernable off-site activity up to 500 µM.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ahn, K.,Johnson, D.S.,Fitzgerald, L.R., et al. Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry 46, 13019-13030 (2007).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | >98% |
| 计算分子量 | 345.4 |
| 分子式 | C22H23N3O |
| CAS号 | 959151-50-9 |
| 稳定性 | ≥ 2 years |
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