N-acetyl-2-carboxy Benzenesulfonamide
货号:
10008284-1mg 基本售价:
182.0 元 规格:
1 mg
产品信息
概述货号 | 10008284-1mg |
描述 | N-acetyl-2-carboxy Benzenesulfonamide is a structural analog of aspirin that acts as a non-selective inhibitor of cyclooxygenase (COX) with a COX-2 selectivity index of 0.23.1 In vitro studies showed that N-acetyl-2-carboxy Benzenesulfonamide is a more potent inhibitor of COX-1/COX-2 with IC50 values of 0.06 µM and 0.25 µM, respectively, than aspirin with IC50 values of 0.35 µM and 2.4 µM, respectively. |
性能供应商 | Cayman |
应用文献 |
1.Chen, Q.H.,Rao, P.N.P., and Knaus, E.E. Design, synthesis, and biological evaluation of N-acetyl-2-carboxybenzenesulfonamides: A novel class of cyclooxygenase-2 (COX-2) inhibitors. Bioorganic & Medicinal Chemistry 13, 2459-2468 (2005).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 243.2 |
分子式 | C9H9NO5S |
CAS号 | 849067-18-1 |
稳定性 | ≥ 2 years |
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