L-NNA
货号：
80220-1g 基本售价：
140.0 元 规格：
1 g
产品信息
概述| 货号 | 80220-1g |
| 描述 | L-NNA is a competitive inhibitor of nitric oxide synthase (NOS) with selectivity for the neuronal and endothelial isoforms of the enzyme. Although L-NAME is much more soluble than L-NNA in aqueous systems, a hydrolysis step is required to “activate” L-NAME, thus adding complexity to an in vivoexperiment.1 L-NNA inhibits nNOS, eNOS, and iNOS with Ki values of 15 nM (bovine), 39 nM (human), and 4.4 µM (mouse), respectively.2,3 |
| 别名 | L-NG-Nitroarginine;NG-nitro-L-Arginine; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Griffith, O.W., and Kilbourn, R.G. Nitric oxide synthase inhibitors: Amino acids. Methods in Enzymology 268, 375-392 (1996).
2.Furfine, E.S.,Harmon, M.F.,Paith, J.E., et al. Selective inhibition of constitutive nitric oxide synthase by L-NG-nitroarginine. Biochemistry 32, 8512-8517 (1993).
3.Garvey, E.P.,Tuttle, J.V.,Covington, K., et al. Purification and characterization of the constitutive nitric oxide synthase from human placenta. Archives of Biochemistry and Biophysics 311, 235-241 (1994).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥99% |
| 计算分子量 | 219.2 |
| 分子式 | C6H13N5O4 |
| CAS号 | 2149-70-4 |
| 稳定性 | ≥ 1 year |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
