Salvinorin A Propionate
货号：
22290-10mg 基本售价：
3920.0 元 规格：
10 mg
产品信息
概述| 货号 | 22290-10mg |
| 描述 | Salvinorin A propionate is a selective partial agonist at κ1-opioid receptors (KOR) with a Ki value of 32.6 nM.1 It inhibits adenylate cyclase (EC50 = 4.7 nM) in HEK293 cells transfected with human KOR.2 It is selective for KORs over µ, δ, and ORL-1 opioid receptors and has no effect at serotonin, dopamine, muscarinic, or adrenergic receptors. In mice, salvinorin A propionate (13 µg, i.c.v.) reduces nociceptive responses in a radiant heat tail-flick assay, though not as potently as salvinorin A (Item No. 11487).1 |
| 别名 | Salvinorinyl-2-propionate; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ansonoff, M.A.,Zhang, J.,Czyzk, T., et al. Antinociceptive and hypothermic effects of salvinorin A are abolished in a novel strain of κ-opioid receptor-1 knockout mice. J. Pharmacol. Exp. Ther. 318(2), 318(312) (2006).
2.Chavkin, C.,Sud, S.,Jin, W., et al. Salvinorin A, an active component of the hallucinogenic sage Salvia divinorum is a highly efficacious κ-opioid receptor agonist: Structural and functional considerations. J. Pharmacol. Exp. Ther. 308(3), 1197-1203 (2004).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 446.5 |
| 分子式 | C24H30O8 |
| CAS号 | 689295-71-4 |
| 稳定性 | ≥ 2 years |
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