ML-324
货号:
14078 基本售价:
4930.0 元 规格:
25 mg
产品信息
概述货号 | 14078 |
描述 | Inhibits JMJD2 histone demethylases (JMJD2 IC50 = 920 nM). Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 M) and abrogates infection. Represses the reactivation of HSV from the latent state in sensory neurons (ref 1). Cell permeable. |
别名 | N-(3-(dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide |
性能供应商 | Active Motif |
运输条件 | Blue Ice |
存放说明 | Store desiccated as supplied at -20°C for up to 1 year. Store solutions at -20°C for up to 1 month. |
纯度 | >98% (TLC); NMR (Conforms) |
计算分子量 | 349.4 |
分子式 | C21H23N3O2 |
CAS号 | Not found |
外观 | Light brown powder. May be dissolved in DMSO (20 mg/ml, warm); Ethanol (6 mg/ml, warm). |
参考文献 | 1. Yu Liang et al. Sci. Transl. Med. 2013, 5:167ra5
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参考图片Chemical structure of ML-324. |