SGC707
货号:
14130 基本售价:
4422.5 元 规格:
25 mg
产品信息
概述货号 | 14130 |
描述 | Pharmacology: Potent and selective allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3)(ref 1). IC50 = 31 nM and selective against 31 other methyltransferases. An extremely useful probe for investigating the role of PRMT3 in normal and pathophysiology. Cell permeable and active in vivo.
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别名 | 1-Isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-yl-ethyl)-urea, SGC707 |
性能供应商 | Active Motif |
运输条件 | Blue Ice |
存放说明 | Store desiccated as supplied at room temperature for up to 2 years. Store solutions at -20°C for up to 3 months. |
纯度 | MP = 233-235°C>98% (TLC); NMR (Conforms) |
计算分子量 | 298.3 |
分子式 | C16H18N4O2 |
CAS号 | 1687736-54-4 |
外观 | Beige crystalline powder. May be dissolved in DMSO (35 mg/ml). |
参考文献 | 1. HU Kaniskan et al. Angew.Chem. Int. Ed. Engl. 2015, 54:5166< |
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